2005•PubMedRequires access

Chromogenic assay of human coagulation factor VIII: statistical comparison of 2 working dilution procedures.

Concepción Alonso, Antonio G. González, G. Frutos

Abstract

The effect of 2 different practices for preparation of working dilutions in the chromogenic substrate method for potency assay of factor VIII was evaluated. In this study the potency of several concentrate materials was shown to be statistically equivalent, whether performing the assay with independent or serial working dilutions.

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Key concepts: Serial dilution, Chromogenic, Potency, Dilution, Chromatography, Chemistry, Medicine, Biochemistry