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Clinical and circulatory effects of oral isosorbide dinitrate in patients with angina during exercise.

P Lauwers, R Tackels

Abstract

Isosorbide dinitrate was given orally to 6 patients with anginal pain on exertion and its effect on exercise capacity, ECG and other hemodynamic parameters was compared with the control values and with the results of a group of 6 patients who received a placebo. The drug seems to affect favourably the working capacity and the ECG on exercise for a longer period than NTG while we do not observe a placebo effect.

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Available abstract

Key concepts: Isosorbide dinitrate, Medicine, Placebo, Angina, Exertion, Hemodynamics, Stable angina, Anesthesia