Effect of organophosphate pesticides on glutaminase synthetase activity in rat brain.
Maitreyi Nag
Abstract
Maitreyi Nag
Abstract
Of the organophosphate pesticides studied, dichlorvos inhibited significantly both, phosphate-activated glutaminase and alpha-keto acid-activated glutaminase, while monocorotophos inhibited moderately alpha-keto acid activated glutaminase in rat brain. Phosphamidon inhibited glutamine synthetase activity negligibly.
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Of the organophosphate pesticides studied, dichlorvos inhibited significantly both, phosphate-activated glutaminase and alpha-keto acid-activated glutaminase, while monocorotophos inhibited moderately alpha-keto acid activated glutaminase in rat brain. Phosphamidon inhibited glutamine synthetase activity negligibly.
Key concepts: Glutaminase, Phosphamidon, Organophosphate, Dichlorvos, Glutamine, Chemistry, Enzyme, Glutamine synthetase