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Effect of organophosphate pesticides on glutaminase synthetase activity in rat brain.

Maitreyi Nag

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Abstract

Of the organophosphate pesticides studied, dichlorvos inhibited significantly both, phosphate-activated glutaminase and alpha-keto acid-activated glutaminase, while monocorotophos inhibited moderately alpha-keto acid activated glutaminase in rat brain. Phosphamidon inhibited glutamine synthetase activity negligibly.

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What this paper is about

Of the organophosphate pesticides studied, dichlorvos inhibited significantly both, phosphate-activated glutaminase and alpha-keto acid-activated glutaminase, while monocorotophos inhibited moderately alpha-keto acid activated glutaminase in rat brain. Phosphamidon inhibited glutamine synthetase activity negligibly.

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Available abstract

Of the organophosphate pesticides studied, dichlorvos inhibited significantly both, phosphate-activated glutaminase and alpha-keto acid-activated glutaminase, while monocorotophos inhibited moderately alpha-keto acid activated glutaminase in rat brain. Phosphamidon inhibited glutamine synthetase activity negligibly.

Key concepts: Glutaminase, Phosphamidon, Organophosphate, Dichlorvos, Glutamine, Chemistry, Enzyme, Glutamine synthetase

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Effect of organophosphate pesticides on glutaminase synthetase activity in rat brain. — Research Paper | ScholarLens