[Relationship between the amylolytic activity of the small intestine and the blood amylolytic activity].

In acute experiments on dogs and rats, soon after ligation of the bile-pancreatic duct or i.v. administration of alpha-amylase, the rise of the amylolytic activity, of amylase excretion with peripheral blood, was shown. The amylolytic activity of the small intestine mucose increased with higher hydrolysis of starch in the abdominal cavity rather than of the membrane. The amylolytic activity greatly increased in apical zone of the fibres rather than in their base, the amylolytic activity of enterocytes suspension increasing too. The great amount of amylase in the blood not only increases the recrement of alpha-amylase by the small intestine, but also induces the synthesis of the intestinal gamma-amylase. This can be observed in adrenalectomized rats, but not in the isolated in vitro small intestine.