RELAPSE OF ANTIBIOTIC‐ASSOCIATED COLITIS AFTER VANCOMYCIN THERAPY
Irene J. Wilkinson, Gordon E. Rich, Brian W. Moore, C. Ross Philpot
Abstract
Irene J. Wilkinson, Gordon E. Rich, Brian W. Moore, C. Ross Philpot
Abstract
Antibiotic-associated colitis, although occasionally fatal, is a disease which is considered to be self-limiting and non-recurring. Recently, specific treatment with oral vancomycin directed at the trigger organism, Clostridium difficile, has been shown to be effective. A case in which antibiotic-associated colitis was treated with vancomycin and subsequently recurred is described. The fact that such relapse can occur indicates that further evaluation of the efficacy of vancomycin is required.
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Antibiotic-associated colitis, although occasionally fatal, is a disease which is considered to be self-limiting and non-recurring. Recently, specific treatment with oral vancomycin directed at the trigger organism, Clostridium difficile, has been shown to be effective. A case in which antibiotic-associated colitis was treated with vancomycin and subsequently recurred is described. The fact that such relapse can occur indicates that further evaluation of the efficacy of vancomycin is required.
Key concepts: Vancomycin, Clostridium difficile, Antibiotics, Colitis, Medicine, Clostridium Difficile Colitis, Antibiotic therapy, Limiting