[Effect of injection of a phosphorylcholine-containing compound from Nippostrongylus brasiliensis on the infestation of the rat by this parasite].
Pierre Pery, A Petit, Jordane Poulain, G Luffau
Abstract
Pierre Pery, A Petit, Jordane Poulain, G Luffau
Abstract
Rats were injected intradermally with the purified phosphorycholine bearing component of the nematode Nippostrongylus brasiliensis. Eight days later they were experimentally infected with 1 X 10(3) infective larvae of the parasite. Compared to the non injected controls we showed a significant decrease in the number of adult worms able to be established in the small intestine. This protective effect seems to be due at least partly to a phenomenom being located between the skin and the lungs of the rats.
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Rats were injected intradermally with the purified phosphorycholine bearing component of the nematode Nippostrongylus brasiliensis. Eight days later they were experimentally infected with 1 X 10(3) infective larvae of the parasite. Compared to the non injected controls we showed a significant decrease in the number of adult worms able to be established in the small intestine. This protective effect seems to be due at least partly to a phenomenom being located between the skin and the lungs of the rats.
Key concepts: Nippostrongylus brasiliensis, Parasite hosting, Nematode, Infestation, Biology, Parasitism, Phosphorylcholine, Larva