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[Karyological study of the continuous cell lines. Comparative analysis of the Hela and Detroit-6 cell lines].

Mikhaĭlova Gr, Rodova Ma, Gadashevich Vn, Demidova Sa, Zhdanov Vm

Abstract

Comparison of the results of the karyologic analysis of two Hela cell sublines (HeLa1 and HeLa2), obtained from different sources, and of Detroit-6 cell line has shown that all the lines contain marker chromosomes characteristic of the HeLa cell line. Detroit-6 cell line marker chromosomes are similar to markers of the HeLa subline (HeLa1). At the same time, part of marker chromosomes in the two sublines of HeLa cell line (HeLa1 and HeLa2) are different. These data show that HeLa1 and Detroit-6 cell lines are more similar than two sublines of the same HeLa cell line.

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Key concepts: HeLa, Cell culture, Cell, Line (geometry), Molecular biology, Biology, Genetics, Mathematics