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Topical metronidazole in the treatment of rosacea.

Veien Nk, Jørgen V. Christiansen, NIELS HJORTH, Henning Schmidt

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Abstract

One percent metronidazole in an emollient cream base was compared with 250 mg oral tetracycline taken twice daily for the treatment of seventy-five patients with rosacea. After eight weeks of treatment there was no statistically significant difference between the results of the two treatments. Tetracycline did have a more rapid onset of effect on papules and pustules. Both treatments were well tolerated.

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What this paper is about

One percent metronidazole in an emollient cream base was compared with 250 mg oral tetracycline taken twice daily for the treatment of seventy-five patients with rosacea. After eight weeks of treatment there was no statistically significant difference between the results of the two treatments. Tetracycline did have a more rapid onset of effect on papules and pustules. Both treatments were well tolerated.

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OpenAlex reports 39 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

One percent metronidazole in an emollient cream base was compared with 250 mg oral tetracycline taken twice daily for the treatment of seventy-five patients with rosacea. After eight weeks of treatment there was no statistically significant difference between the results of the two treatments. Tetracycline did have a more rapid onset of effect on papules and pustules. Both treatments were well tolerated.

Key concepts: Rosacea, Medicine, Metronidazole, Tetracycline, Dermatology, Significant difference, Acne, Antibiotics

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