Cystic echinococcosis: progress and limits in epidemiology and immunodiagnosis.
Andrea Siracusano, F. Bruschi
Abstract
Andrea Siracusano, F. Bruschi
Abstract
This study discusses the epidemiology and immunodiagnosis of cystic echinococcosis (caused by Echinococcus granulosus). Despite the development of molecular methods to prepare antigens, nowadays there is no standard, highly sensitive, and specific test available for antibody detection in cystic echinococcosis. Furthermore, because serological tests can give only a limited support to clinical findings there is a clear need for new advances in immunodiagnosis of E. granulosus infection.
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This study discusses the epidemiology and immunodiagnosis of cystic echinococcosis (caused by Echinococcus granulosus). Despite the development of molecular methods to prepare antigens, nowadays there is no standard, highly sensitive, and specific test available for antibody detection in cystic echinococcosis. Furthermore, because serological tests can give only a limited support to clinical findings there is a clear need for new advances in immunodiagnosis of E. granulosus infection.
Key concepts: Echinococcus granulosus, Cystic echinococcosis, Echinococcosis, Serology, Epidemiology, Medicine, Immunology, Biology