1982•PubMedRequires access

[HLA-A-, B- and C-geno- and haplotype frequency in Vienna. Analysis of phenotype data].

H Arnold, Mayr Wr

Abstract

The HLA-A-A, B, C gene and haplotype frequencies have been calculated by using a computer-algorithm from the HLA phenotypes of 3000 unrelated, healthy inhabitants of Vienna. The frequencies are in good agreement with the figures obtained in a family study. The analysis of the linkage disequilibria involving alleles at 2 out of the 3 loci or at all the 3 loci shows that the disequilibrium between alleles of 2 loci (HLA-A, B, HLA-B, C and HLA-A, C) is stronger than the one observed with alleles at the 3 loci (HLA-A, B, C).

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Haplotype, Linkage disequilibrium, Genetics, Allele, Human leukocyte antigen, Biology, Phenotype, Allele frequency