Drug therapy for seizures.

Phenytoin, valproic acid, carbamazepine, phenobarbital, primidone, and ethosuximide are important in anticonvulsant therapy. Each drug's structure determines its properties and its activity against particular seizure types. Single-drug therapy is generally preferable to multiple-drug therapy. Absorption, half-life, metabolism, and other pharmacokinetic characteristics are important considerations in the selection of an anticonvulsant drug.