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[Contribution of hepatic scintigraphy with Tc99m blood cells to the imaging diagnosis of cavernous hemangioma. Results in 48 patients].

C Ceballos, C Isla, Miravete Mi, E. Cordoba, Teresa Baringo, J M Artigas

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Abstract

Cavernous hemangiomas are the most common benign tumours of the liver, being the liver the most frequent organ affected by this lesions. We report 48 patients who underwent 99mTc-red blood cell (RBC) scintigraphy, after ultrasound or tomographic appearance of cavernous hemangioma. Scintigraphy findings in 29 of 48 patients (60.4%) were typical of cavernous hemangioma, hemangioma-positives, after scintigraphy (all true-positives). On clinical, ultrasound and in one case after surgery (exploratory laparotomy) the follow up was positive for hemangioma. Specificity of 100%. In the remaining 19 patients (39.6%) where hemangioma-negative lesions, 17 of 19 where true negatives and the remaining 2 where angiomas false-negatives, both of them were small lesions. The sensitivity for hemangiomas was 89.4%. To conclude with we would like to enhance the high specificity and sensitivity of 99mTc-red blood cell scintigraphy on the diagnosis of cavernous hepatic hemangioma (CHH). We highlight the utility of this specific imaging technique in the final diagnosis of CHH not requiring other invasive diagnosis tests, such as laparoscopy that in our study proved to be unnecessary.

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Cavernous hemangiomas are the most common benign tumours of the liver, being the liver the most frequent organ affected by this lesions. We report 48 patients who underwent 99mTc-red blood cell (RBC) scintigraphy, after ultrasound or tomographic appearance of cavernous hemangioma. Scintigraphy findings in 29 of 48 patients (60.4%) were typical of cavernous hemangioma, hemangioma-positives, after scintigraphy (all true-positives). On clinical, ultrasound and in one case after surgery (exploratory laparotomy) the follow up was positive for hemangioma. Specificity of 100%. In the remaining 19 patients (39.6%) where hemangioma-negative lesions, 17 of 19 where true negatives and the remaining 2 where angiomas false-negatives, both of them were small lesions. The sensitivity for hemangiomas was 89.4%. To conclude with we would like to enhance the high specificity and sensitivity of 99mTc-red blood cell scintigraphy on the diagnosis of cavernous hepatic hemangioma (CHH). We highlight the utility of this specific imaging technique in the final diagnosis of CHH not requiring other invasive diagnosis tests, such as laparoscopy that in our study proved to be unnecessary.

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Available abstract

Cavernous hemangiomas are the most common benign tumours of the liver, being the liver the most frequent organ affected by this lesions. We report 48 patients who underwent 99mTc-red blood cell (RBC) scintigraphy, after ultrasound or tomographic appearance of cavernous hemangioma. Scintigraphy findings in 29 of 48 patients (60.4%) were typical of cavernous hemangioma, hemangioma-positives, after scintigraphy (all true-positives). On clinical, ultrasound and in one case after surgery (exploratory laparotomy) the follow up was positive for hemangioma. Specificity of 100%. In the remaining 19 patients (39.6%) where hemangioma-negative lesions, 17 of 19 where true negatives and the remaining 2 where angiomas false-negatives, both of them were small lesions. The sensitivity for hemangiomas was 89.4%. To conclude with we would like to enhance the high specificity and sensitivity of 99mTc-red blood cell scintigraphy on the diagnosis of cavernous hepatic hemangioma (CHH). We highlight the utility of this specific imaging technique in the final diagnosis of CHH not requiring other invasive diagnosis tests, such as laparoscopy that in our study proved to be unnecessary.

Key concepts: Medicine, Hemangioma, Scintigraphy, Radiology, Exploratory laparotomy, Ultrasound, False positive paradox, Cavernous hemangiomas

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[Contribution of hepatic scintigraphy with Tc99m blood cells to the imaging diagnosis of cavernous hemangioma. Results in 48 patients]. — Research Paper | ScholarLens