Colonization of a human intestine by four different genotypes of Lactobacillus acidophilus.
Pier Giacomo Sarra, Franco Dellaglio
Abstract
Pier Giacomo Sarra, Franco Dellaglio
Abstract
To understand the effect on a human host suffering from intestinal disorders we supplied non fat milk cultures of Lactobacillus acidophilus for 25 days. The picture of the faeces bacterial count was completely different before and after treatment and we noticed increases in lactobacilli, bifidobacteria and coliforms while the clostridia decreased. The lactobacilli treatment solved the diarrohea problem. Of the four genetic lines of L. acidophilus supplied only D179, isolated from calf faeces, and ATCC 4356 of human origin were found able to colonize the intestine of the little girl, while 255S isolated from swine and D328 isolated from calf faeces, did not find favourable growth conditions.
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To understand the effect on a human host suffering from intestinal disorders we supplied non fat milk cultures of Lactobacillus acidophilus for 25 days. The picture of the faeces bacterial count was completely different before and after treatment and we noticed increases in lactobacilli, bifidobacteria and coliforms while the clostridia decreased. The lactobacilli treatment solved the diarrohea problem. Of the four genetic lines of L. acidophilus supplied only D179, isolated from calf faeces, and ATCC 4356 of human origin were found able to colonize the intestine of the little girl, while 255S isolated from swine and D328 isolated from calf faeces, did not find favourable growth conditions.
Key concepts: Lactobacillus acidophilus, Clostridia, Feces, Biology, Colonization, Microbiology, Lactobacillaceae, Large intestine