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Increased alpha-fetoprotein biosynthesis in rats following DL-ethionine and carbon tetrachloride injuries.

Akiko Watanabe

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Abstract

The incorporation of 14C-leucine into alpha-fetoprotein (AFP) in serum and liver extracts from DL-ethionine and carbon tetrachloride (CCl4)-injured rats was measured directly by using an immunochemical technique. The maximum value with nearly 10-fold increases of serum AFP was obtained in 3 days of both treatments. However, no significant increase in the immunoprecipitable AFP in liver extracts was detected under these conditions.

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What this paper is about

The incorporation of 14C-leucine into alpha-fetoprotein (AFP) in serum and liver extracts from DL-ethionine and carbon tetrachloride (CCl4)-injured rats was measured directly by using an immunochemical technique. The maximum value with nearly 10-fold increases of serum AFP was obtained in 3 days of both treatments. However, no significant increase in the immunoprecipitable AFP in liver extracts was detected under these conditions.

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Available abstract

The incorporation of 14C-leucine into alpha-fetoprotein (AFP) in serum and liver extracts from DL-ethionine and carbon tetrachloride (CCl4)-injured rats was measured directly by using an immunochemical technique. The maximum value with nearly 10-fold increases of serum AFP was obtained in 3 days of both treatments. However, no significant increase in the immunoprecipitable AFP in liver extracts was detected under these conditions.

Key concepts: Ethionine, Carbon tetrachloride, Alpha (finance), Leucine, Alpha-fetoprotein, CCL4, Internal medicine, CARBON TETRACHLORIDE POISONING

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Increased alpha-fetoprotein biosynthesis in rats following DL-ethionine and carbon tetrachloride injuries. — Research Paper | ScholarLens