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Bacillaemia and Mycobacterium leprae cell wall antigen in paucibacillary leprosy.

Inderjeet Kaur, S Kaur, Sharma Vk, Navneet Agnihotri, Chetana V. Vaishnavi, Nirmal Kumar Ganguly

Abstract

A study was undertaken to estimate bacillaemia and M. leprae antigen detection in 54 paucibacillary leprosy patients (TT, BT). Acid-fast bacilli were detected in the blood of 14.8% patients of borderline tuberculoid (BT) leprosy. M. leprae antigen was demonstrated in 48.2% patients of BT leprosy. Slit-skin smears were negative in all these patients. At the end of treatment (6 months of WHO-MDT) all the follow-up blood samples were negative for both bacillaemia and M. leprae antigen in the serum.

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Key concepts: Leprosy, Mycobacterium leprae, Tuberculoid leprosy, Medicine, Antigen, Immunology, Acid-fast, Bacilli