Immunohistochemical analysis of soft tissue sarcomas. Comparisons with electron microscopy.
Wick Mr, Swanson Pe, Manivel Jc
Abstract
Wick Mr, Swanson Pe, Manivel Jc
Abstract
Soft tissue sarcomas are capable of causing diagnostic bewilderment for the surgical pathologist, because of their diversity of differentiation and overlapping histologic appearances. Immunohistochemical studies provide a means whereby this confusion can be resolved in many cases, and electron microscopy also may play a useful role in this process. This overview presents a summary of results of these 2 adjuvant modalities of pathologic analysis, as applied to the spectrum of malignant soft tissue neoplasms.
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Soft tissue sarcomas are capable of causing diagnostic bewilderment for the surgical pathologist, because of their diversity of differentiation and overlapping histologic appearances. Immunohistochemical studies provide a means whereby this confusion can be resolved in many cases, and electron microscopy also may play a useful role in this process. This overview presents a summary of results of these 2 adjuvant modalities of pathologic analysis, as applied to the spectrum of malignant soft tissue neoplasms.
Key concepts: Pathology, Immunohistochemistry, Soft tissue, Confusion, Soft tissue pathology, Medicine, Electron microscope, Optics