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Chlorambucil in the treatment of intractable Uveitis associated with juvenile chronic arthritis.

Palmer Rg, Kanski Jj, Ansell Bm

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Abstract

The response to prolonged low dose chlorambucil for chronic active uveitis in 6 patients with juvenile chronic arthritis and one patient with juvenile ankylosing spondylitis is described. Only 2 patients were judged to have had longterm benefit from treatment in both eyes and one had a transient benefit in one eye. Drug induced adverse effects occurred in 3 patients.

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What this paper is about

The response to prolonged low dose chlorambucil for chronic active uveitis in 6 patients with juvenile chronic arthritis and one patient with juvenile ankylosing spondylitis is described. Only 2 patients were judged to have had longterm benefit from treatment in both eyes and one had a transient benefit in one eye. Drug induced adverse effects occurred in 3 patients.

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OpenAlex reports 30 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The response to prolonged low dose chlorambucil for chronic active uveitis in 6 patients with juvenile chronic arthritis and one patient with juvenile ankylosing spondylitis is described. Only 2 patients were judged to have had longterm benefit from treatment in both eyes and one had a transient benefit in one eye. Drug induced adverse effects occurred in 3 patients.

Key concepts: Medicine, Chlorambucil, Ankylosing spondylitis, Uveitis, Arthritis, Juvenile, Juvenile chronic arthritis, Juvenile rheumatoid arthritis

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Chlorambucil in the treatment of intractable Uveitis associated with juvenile chronic arthritis. — Research Paper | ScholarLens