Chlorambucil in the treatment of intractable Uveitis associated with juvenile chronic arthritis.
Palmer Rg, Kanski Jj, Ansell Bm
Abstract
Palmer Rg, Kanski Jj, Ansell Bm
Abstract
The response to prolonged low dose chlorambucil for chronic active uveitis in 6 patients with juvenile chronic arthritis and one patient with juvenile ankylosing spondylitis is described. Only 2 patients were judged to have had longterm benefit from treatment in both eyes and one had a transient benefit in one eye. Drug induced adverse effects occurred in 3 patients.
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The response to prolonged low dose chlorambucil for chronic active uveitis in 6 patients with juvenile chronic arthritis and one patient with juvenile ankylosing spondylitis is described. Only 2 patients were judged to have had longterm benefit from treatment in both eyes and one had a transient benefit in one eye. Drug induced adverse effects occurred in 3 patients.
Key concepts: Medicine, Chlorambucil, Ankylosing spondylitis, Uveitis, Arthritis, Juvenile, Juvenile chronic arthritis, Juvenile rheumatoid arthritis