STUDIES ON URINARY TRACT INFECTION REPORT II

Using as sources of isolation urine specimens from the 425 cases of urosis observed during the period 1962-1965, cultivation was done 464 times with a resultant yield of 493 strains. The sensitivity test of these strains with antibiotics and sulfa drugs revealed the following results:1) Among the isolated 493 strains, Escherichia Coli occupied 31.6%, Staphylococcus 31.0%, Proteus 18.1%, Streptococcus 8.9%, Bacillus Pyocyaneus 6.1 and unidentifiable Gram-negative rods 4.1%.2) As compared to the above-mentioned ranks by strains in primary infection, an increase in Proteus and bacillus pyocyaneus was marked in secondary infection.3) When the 493 strains were considered in terms of diseases and microorganisms, the rate of detection of Eschericha Coli was high for ureteropathia, renopathy, prostatomegaly etc. Staphylococcus was detected at a high frequency in urethral diseases and cystic diseases. Proteus was frequently found in cystic diseases, renopathy, tumor and calculosis; bacillus pyocyaneus was frequently detected in tuberculosis, tumor, renopathy and calculosis.4) As to 493 strains which could not be judged by cultivation and identification, 20 (4.1%) were detected. These strains had not been detected at all in primary infection.5) The distribution of the above unidentifiable Gram-negative rods by diseases agreed with that of bacillus pyocyaneus.6) Regarding the sensitivity test, a reduction in sensitivity of the microorganisms to antibiotics and sulfa drugs was remarkable.7) The resistance of antibiotics and sulfa drugs against the isolated microorganisms showed multi-resistance in many instances.