1987•PubMedRequires access
[Morphology and histogenesis of yolk sac tumors in the testis].
Romanenko Am, Iu V Persidskiĭ
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Abstract
The differentiation of yolk sac tumor cells was similar to the processes of development of embryonic and extraembryonic endoderm during the first 7 wk after cleavage. Two ways of yolk sac tumor histogenesis are discussed: differentiation of embryonal carcinoma cells, and redifferentiation of the polypotent undifferentiated anaplastic seminoma cells. Histogenesis features described may be responsible for aggressive nature and high malignancy of yolk sac tumors.