[Diagnostic efficiency of histological and simple microbiological tests for Helicobacter pylori detection in a community hospital].
Emmanuel Mitry, M Leneveu, Vitte Rl, L Wesenfelder, Carole Felsenheld, C Eugène, Anne Bergue
Abstract
Emmanuel Mitry, M Leneveu, Vitte Rl, L Wesenfelder, Carole Felsenheld, C Eugène, Anne Bergue
Abstract
The objective of this study was to compare histology and microbiology (direct method, urease test, culture) for the detection of Helicobacter pylori in antral biopsies. Thirty-six patients, aged between 18 and 82, with a peptic ulcer (active or not), or gastritis or duodenitis were studied. Eighteen patients (50%) had a positive culture, 17 (47%) had a positive urease test, 16 (41%) had positive direct microbiology and 15 (42%) had positive histology. Correlation between histology and culture was 84%. This study confirms the good sensitivity of histology and the urease test for the detection of Helicobacter pylori. Combination of both methods could optimise detection of the organism.
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The objective of this study was to compare histology and microbiology (direct method, urease test, culture) for the detection of Helicobacter pylori in antral biopsies. Thirty-six patients, aged between 18 and 82, with a peptic ulcer (active or not), or gastritis or duodenitis were studied. Eighteen patients (50%) had a positive culture, 17 (47%) had a positive urease test, 16 (41%) had positive direct microbiology and 15 (42%) had positive histology. Correlation between histology and culture was 84%. This study confirms the good sensitivity of histology and the urease test for the detection of Helicobacter pylori. Combination of both methods could optimise detection of the organism.
Key concepts: Rapid urease test, Histology, Helicobacter pylori, Gastritis, Duodenitis, Spirillaceae, Gastroenterology, Medicine