1999•PubMedOpen access

Gastric neuroendocrine cells and secretory products.

Kjell Öberg

Abstract

The ECL cell is the most common cell type in the oxyntic mucosa of the stomach. It is producing a number of peptides and amines where histamine and chromogranin A seems to be the most important and abundant products. Recent data indicate a direct correlation between ECL-cell mass and circulating chromogranin A levels. Chromogranin A and its splice products might serve as growth promoting agents in ECL-cell hyperplasia or gastric carcinoids.

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Available abstract

Key concepts: Chromogranin A, Enterochromaffin-like cell, Histamine, Enterochromaffin cell, Gastrin, Stomach, Gastric mucosa, Cell type