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Studies on the Chinese Crude Drug "Forsythiae Fructus." VIII. On Isolation of Phenylpropanoid Glycosides from Fruits of Forsythia koreana and Their Antibacterial Activity

Shizuka Kitagawa, Sansei Nishibe, Hisae Baba

Abstract

It was revealed that the fruits of Forsythia koreana NAKAI (Oleaceae) contain four phenylpropanoid glycosides, suspensaside, β-hydroxyacteoside, forsythiaside and acteoside. Antibacterial activity of phenolic compounds isolated from Forsythia fruits and the aqueous extracts of the fruits were examined. Four phenylpropanoid glycosides and the aqueous extracts of the fruits of Forsythia suspensa showed high antibacterial activity against Staphylococcus aureus TERASHIMA.

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Key concepts: Forsythia, Phenylpropanoid, Glycoside, Oleaceae, Traditional medicine, Chemistry, Verbascoside, Antibacterial activity