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[Effect of dissolved heterologous collagen on human platelet aggregation].

U Joos, G Ochs

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Abstract

Our in vitro experiments showed the positive effect of a solution containing collagen fleece on aggregation in platelet-rich plasma of healthy subjects and of patients with thrombocytic coagulation disturbances. The added collagen directly affects the adhesion and aggregation of the platelets. The platelets then complete the process of primary hemostasis by forming a thrombus and the plasmatic "intrinsic system" is started. These results have already been implemented at the practical level.

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What this paper is about

Our in vitro experiments showed the positive effect of a solution containing collagen fleece on aggregation in platelet-rich plasma of healthy subjects and of patients with thrombocytic coagulation disturbances. The added collagen directly affects the adhesion and aggregation of the platelets. The platelets then complete the process of primary hemostasis by forming a thrombus and the plasmatic "intrinsic system" is started. These results have already been implemented at the practical level.

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Available abstract

Our in vitro experiments showed the positive effect of a solution containing collagen fleece on aggregation in platelet-rich plasma of healthy subjects and of patients with thrombocytic coagulation disturbances. The added collagen directly affects the adhesion and aggregation of the platelets. The platelets then complete the process of primary hemostasis by forming a thrombus and the plasmatic "intrinsic system" is started. These results have already been implemented at the practical level.

Key concepts: Platelet, Thrombus, Coagulation, Hemostasis, Platelet aggregation, Heterologous, Chemistry, Adhesion

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