LEUKOCYTE ANTIGENS IN RENAL TRANSPLANTATION 8. SUCCESSFUL RENAL TRANSPLANTATION IN THE PRESENCE OF A POSITIVE CROSS MATCH

Renal transplantation in the presence of preformed antibodies against donor histocompatibility antigens (positive cross match) almost inevitably results in immediate failure of the graft. The presence of a positive cross match is considered a contraindication to renal transplantation. A well-documented case of a successful renal transplant (creatinine clearance of 80 ml/min. at seven months) in the presence of a positive cross-match is described, but it is nevertheless recommended that a positive cross match should be considered a definite contraindication to transplantation.