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[Antimycotic activity in vitro and in vivo of 5-fluorocytosine on pathogenic strains of Candida albicans and Cryptococcus neoformans].

Costa Al, Andrea Valenti, Grégory Da Costa, F Calogero

Abstract

The authors have analyzed the 5 Fluoro Cytosine (5FC) activity on strains of Candida albicans and Criptococcus neoformans, both in vitro and in vivo. In vitro the minimal inhibitory concentration (MIC) was determined; in vivo tests of pathogenicity on rabbit and mouse have been executed. The various findings obtained have shown a strong activity of the 5FC on strains of Candida and Criptococcus.

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Available abstract

Key concepts: Cryptococcus neoformans, Candida albicans, In vivo, Microbiology, In vitro, Biology, Cryptococcus, Cryptococcosis