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[Serotype distribution of Actinobacillus actinomycetemcomitans].

Z Wang, Shuang Yang, J Shang

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Abstract

A total of 131 Actinobacillus actinomycetemcomitans clinical strains from 28 periodontally healthy or diseased subjects were serologically categorized by indirect enzyme-linked immnosorbent assay. Sepecies-specific and serotype b, c-specific monoclonal antibodies against Actinobacillus actinomycetemcomitans were used. Preliminary data revealed that each subject harbored only one serotype of Actinobacillus actinomycetemcomitans. The distribution of serotype a, b and c were respectively 11%, 21% and 68%, both of periodontally healthy subjects harbered serotype b, 7 of 9 juvenile periodontitis subjects harbered serotype c, 12 of the other subjects which included 3 adult periodontitis and 14 gingivitis harbered serotype c.

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What this paper is about

A total of 131 Actinobacillus actinomycetemcomitans clinical strains from 28 periodontally healthy or diseased subjects were serologically categorized by indirect enzyme-linked immnosorbent assay. Sepecies-specific and serotype b, c-specific monoclonal antibodies against Actinobacillus actinomycetemcomitans were used. Preliminary data revealed that each subject harbored only one serotype of Actinobacillus actinomycetemcomitans. The distribution of serotype a, b and c were respectively 11%, 21% and 68%, both of periodontally healthy subjects harbered serotype b, 7 of 9 juvenile periodontitis subjects harbered serotype c, 12 of the other subjects which included 3 adult periodontitis and 14 gingivitis harbered serotype c.

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Available abstract

A total of 131 Actinobacillus actinomycetemcomitans clinical strains from 28 periodontally healthy or diseased subjects were serologically categorized by indirect enzyme-linked immnosorbent assay. Sepecies-specific and serotype b, c-specific monoclonal antibodies against Actinobacillus actinomycetemcomitans were used. Preliminary data revealed that each subject harbored only one serotype of Actinobacillus actinomycetemcomitans. The distribution of serotype a, b and c were respectively 11%, 21% and 68%, both of periodontally healthy subjects harbered serotype b, 7 of 9 juvenile periodontitis subjects harbered serotype c, 12 of the other subjects which included 3 adult periodontitis and 14 gingivitis harbered serotype c.

Key concepts: Actinobacillus, Serotype, Microbiology, Gingivitis, Biology, Monoclonal antibody, Periodontitis, Virology

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