Thrombolytische Stoffen En Farmaca Aancewend Om De Fibrinolytische Activiteit In De Bloedbaan Te Verhocen

SummaryDifferent products are claimed to be thrombolytic. Some of them are active in vitro (fibrinoylsin, urokinase, streptokinase) and others would produce a fibrinolytic activity in the blood after injection (anticoagulants, nicotinic acid, pyrogens, etc.).In order to evaluate the therapeutic value of these drugs in the treatment of thrombo-cmbolic accidents four questions were studied for each product :1) activity in vitro;2) activity after administration in vivo;3) side effects;4) dissolution of an in vivo clot.