2012•PubMedRequires access

[Chemical constituents from Coptis chinensis].

Zhifeng Li, Qi Wang, Yulin Feng, Xiaojian Luo, Mei-mei Fan, Shilin Yang

Abstract

OBJECTIVE: To study the chemical constituents of Coptis chinensis. METHODS: The compounds were separated and purified by column chromatography and their structures were identified by spectroscopic methods. RESULTS: Seven compounds were isolated from the chloroform extract of Coptis chinensis, whose structures were determined as worenine (1),8,9-dihydroxy-1,5,6, 10b-tetrahydro-2H-pyrrolo[2,1 -alpha] isoquinolin-3-one (2),(+/-) -5,5'-dimethoxy-lariciresinol (3),3,4-dihydroxy-phenylethylalcohol(4), methyl-5-O-feruloylquinate (5), ethyl-5-O- feruloylquinate (6), apocynol (7). CONCLUSION: Compounds (3) is isolated from this genus for the first time, compounds (5), (6), (7) are isolated from this plant for the first time.

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Key concepts: Coptis chinensis, Coptis, Chloroform, Chemical constituents, Chemistry, Chromatography, Column chromatography, Chemical structure