Clofazimine in the treatment of dapsone resistant leprosy.
Taylor Pm, Alexander Rabe
Abstract
Taylor Pm, Alexander Rabe
Abstract
Dapsone resistant patients treated with clofazimine 100 mg daily show a consistent response to treatment. Concern is expressed regarding the prolonged persistence of viable organisms during treatment, with the attendant risk of further resistance developing. The importance of prevention of this problem is discussed.
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Dapsone resistant patients treated with clofazimine 100 mg daily show a consistent response to treatment. Concern is expressed regarding the prolonged persistence of viable organisms during treatment, with the attendant risk of further resistance developing. The importance of prevention of this problem is discussed.
Key concepts: Clofazimine, Dapsone, Leprosy, Medicine, Persistence (discontinuity), Drug resistance, Dermatology, Microbiology