[Electroencephalographic observations after therapy with vincristine (author's transl)].

A direct cytotoxic effect of vincristine on the neurons, especially the cerebral cortex is discussed in the literature. In 188 patients treated with vincristine we saw no so called "Vincristine-induced Encephalopathy". In 67 children investigated 5 weeks up to 2 years after the last vincristine-injection we found no changes in EEG-tracings which could be discussed as vincristine-induced.