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[The diagnostic value of the assay of lactate dehydrogenese combined with other tumor markers in ovarian cancer].

Tang Bj, Li L, Jianmin Xu

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Abstract

Thirty-five cases of ovarian cancer, 35 ovarian benign tumors, 31 other gynecologic cancer and 35 normal controls were assayed for LDH, LDH-isoenzyme, SA, CEA, beta 2-MG and AKP. The results showed: (1) The average content of tumor markers in ovarian cancer was higher than benign tumor and healthy controls. (2) The positive rate of tumor markers in stage I and II patients of ovarian cancer was lower than in stage III and IV. (3) In the tumor markers, the diagnostic value of LDH-isoenzyme for ovarian cancer was best. (4) Combined assaying LDH, LDH-isoenzyme and SA was superior to using one marker for the diagnosis of ovarian cancer.

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What this paper is about

Thirty-five cases of ovarian cancer, 35 ovarian benign tumors, 31 other gynecologic cancer and 35 normal controls were assayed for LDH, LDH-isoenzyme, SA, CEA, beta 2-MG and AKP. The results showed: (1) The average content of tumor markers in ovarian cancer was higher than benign tumor and healthy controls. (2) The positive rate of tumor markers in stage I and II patients of ovarian cancer was lower than in stage III and IV. (3) In the tumor markers, the diagnostic value of LDH-isoenzyme for ovarian cancer was best. (4) Combined assaying LDH, LDH-isoenzyme and SA was superior to using one marker for the diagnosis of ovarian cancer.

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Available abstract

Thirty-five cases of ovarian cancer, 35 ovarian benign tumors, 31 other gynecologic cancer and 35 normal controls were assayed for LDH, LDH-isoenzyme, SA, CEA, beta 2-MG and AKP. The results showed: (1) The average content of tumor markers in ovarian cancer was higher than benign tumor and healthy controls. (2) The positive rate of tumor markers in stage I and II patients of ovarian cancer was lower than in stage III and IV. (3) In the tumor markers, the diagnostic value of LDH-isoenzyme for ovarian cancer was best. (4) Combined assaying LDH, LDH-isoenzyme and SA was superior to using one marker for the diagnosis of ovarian cancer.

Key concepts: Ovarian cancer, Tumor marker, Cancer, Medicine, Internal medicine, Stage (stratigraphy), Ovarian tumor, Isozyme

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[The diagnostic value of the assay of lactate dehydrogenese combined with other tumor markers in ovarian cancer]. — Research Paper | ScholarLens