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Preparation and characterization of insulin of carp (Cyprinus carpio).

Rapoport Ta, Kohnert Kd, S. Knospe, Ansgar Lukowsky, Siegfried Prehn, H. Schäfer, S Schmidt, M Ziegler

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Abstract

Insulin of carp (Cyprinus carpio) was isolated and crystallized. The insulin was biologically active in two tests; it decreased the blood glucose level and stimulated 14CO2-formation from glucose. The chemical properties are similar to those of insulins from other species. The insulins of carp and of mammals differ greatly immunologically. Antibodies against carp insulin crossreact with carp proinsulin.

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What this paper is about

Insulin of carp (Cyprinus carpio) was isolated and crystallized. The insulin was biologically active in two tests; it decreased the blood glucose level and stimulated 14CO2-formation from glucose. The chemical properties are similar to those of insulins from other species. The insulins of carp and of mammals differ greatly immunologically. Antibodies against carp insulin crossreact with carp proinsulin.

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Available abstract

Insulin of carp (Cyprinus carpio) was isolated and crystallized. The insulin was biologically active in two tests; it decreased the blood glucose level and stimulated 14CO2-formation from glucose. The chemical properties are similar to those of insulins from other species. The insulins of carp and of mammals differ greatly immunologically. Antibodies against carp insulin crossreact with carp proinsulin.

Key concepts: Cyprinus, Carp, Proinsulin, Insulin, Internal medicine, Endocrinology, Common carp, Antibody

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