2011•PubMedRequires access

[Influence of hydrophiling agents on gel formation rate on Carbopol base].

Maria Szcześniak, Janusz Pluta

Abstract

The aim of the study was to assess the impact of substrate composition on the physicochemical and pharmaceutical availability of hydrocortisone. Gels prepared on the basis of contained varying amounts of Carbopol propylene glycol-1,2, and polyethylene glycol 200. Applied hydrophilic substances affect the diversity of hydrocortisone half release times from hydrogels.

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Key concepts: Polyethylene glycol, Self-healing hydrogels, Polyvinyl alcohol, Chemistry, Chemical engineering, Polymer chemistry, Chromatography, Organic chemistry