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Studies on Chemical Protectors against Radiation. XIX. Influence of Whole Body Irradiation by Soft X-ray on Mouse Skin

Masato Shinoda, Setsuko Ohta, Yukitoshi Hayase, Motoyuki Shimizu

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Abstract

Skin damage in mice given whole-body irradiation of 30 kVp soft X-ray on the back was observed for 40 days. Depilation and ulceration were seen after irradiation of 2400-12000 R, and the time of appearance and duration of such symptoms were found to be in inverse proportion to be in inverse proportion to the irradiated dose. For irradiation of 3000-7000 R, damages quantitated from the irradiation dose and score table showed a significant linear relation. Irradiation of 4000 R showed hardly any effect on peripheral erythrocytes and total leucotytes.

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Skin damage in mice given whole-body irradiation of 30 kVp soft X-ray on the back was observed for 40 days. Depilation and ulceration were seen after irradiation of 2400-12000 R, and the time of appearance and duration of such symptoms were found to be in inverse proportion to be in inverse proportion to the irradiated dose. For irradiation of 3000-7000 R, damages quantitated from the irradiation dose and score table showed a significant linear relation. Irradiation of 4000 R showed hardly any effect on peripheral erythrocytes and total leucotytes.

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Available abstract

Skin damage in mice given whole-body irradiation of 30 kVp soft X-ray on the back was observed for 40 days. Depilation and ulceration were seen after irradiation of 2400-12000 R, and the time of appearance and duration of such symptoms were found to be in inverse proportion to be in inverse proportion to the irradiated dose. For irradiation of 3000-7000 R, damages quantitated from the irradiation dose and score table showed a significant linear relation. Irradiation of 4000 R showed hardly any effect on peripheral erythrocytes and total leucotytes.

Key concepts: Irradiation, Nuclear medicine, X-ray, Soft X-rays, Whole body irradiation, Soft tissue, Chemistry, Radiochemistry

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