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[Use of clonidine in the prevention of alcohol withdrawal syndrome].

M Mondavio, Ghiazza Gf

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Abstract

Clonidine, an effective antihypertensive drug acting on central presynaptic alpha 2-adrenoreceptors, is commonly used in opiate withdrawal. There is recent evidence of advantages in using clonidine also in alcohol withdrawal. The results of a randomized study on 44 alcoholics, admitted without withdrawal symptoms, are shown. The alcohol withdrawal syndrome appeared in 50% of the patients in the placebo group and in 9% of the clonidine treated patients. Clonidine is an effective tool in the hospital preventive treatment of alcohol withdrawal.

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What this paper is about

Clonidine, an effective antihypertensive drug acting on central presynaptic alpha 2-adrenoreceptors, is commonly used in opiate withdrawal. There is recent evidence of advantages in using clonidine also in alcohol withdrawal. The results of a randomized study on 44 alcoholics, admitted without withdrawal symptoms, are shown. The alcohol withdrawal syndrome appeared in 50% of the patients in the placebo group and in 9% of the clonidine treated patients. Clonidine is an effective tool in the hospital preventive treatment of alcohol withdrawal.

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OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Clonidine, an effective antihypertensive drug acting on central presynaptic alpha 2-adrenoreceptors, is commonly used in opiate withdrawal. There is recent evidence of advantages in using clonidine also in alcohol withdrawal. The results of a randomized study on 44 alcoholics, admitted without withdrawal symptoms, are shown. The alcohol withdrawal syndrome appeared in 50% of the patients in the placebo group and in 9% of the clonidine treated patients. Clonidine is an effective tool in the hospital preventive treatment of alcohol withdrawal.

Key concepts: Clonidine, Placebo, Alcohol withdrawal syndrome, Medicine, Anesthesia, Withdrawal syndrome, Alcohol, Drug withdrawal

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[Use of clonidine in the prevention of alcohol withdrawal syndrome]. — Research Paper | ScholarLens