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[Adoptive immunotherapy of malignant diseases using normal allogeneic LAK cells].

Yuta Kimoto, Yasunori Tanji, T Tanaka, T Taguchi

Abstract

Allogeneic LAK cells induced from PBL of normal donors were used for adoptive immunotherapy of malignant diseases. The possibility of an antibody against allogeneic LAK cells was suggested. However, no immune reaction was observed and LAK activity was maintained in vitro in the presence of patient's plasma sampled during the course of therapy.

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Available abstract

Key concepts: Adoptive immunotherapy, Lymphokine-activated killer cell, Adoptive cell transfer, Immunotherapy, Immunology, Medicine, Antibody, In vitro