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Aspiration and exfoliative cytology, including ultrastructure, of a malignant granular-cell tumor.

Geisinger Kr, E H Kawamoto, Richard B. Marshall, Ernest T. Ahl, M R Cooper

Abstract

The cytopathologic features of a malignant granular cell tumor in both exfoliative and aspiration cytopreparations included isolated cells with low nuclear-cytoplasmic ratios and abundant, diffusely granular cytoplasm. Transmission electron microscopy revealed the diagnostic secondary lysosomes in the neoplastic cells.

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Key concepts: Exfoliative cytology, Ultrastructure, Cytoplasm, Pathology, Medicine, Cytopathology, Cytology, Granular cell tumor