Bullous pemphigoid in lepromatous leprosy.
Devinder Mohan Thappa, M V Rao, B R Garg, C Ratnakar
Abstract
Devinder Mohan Thappa, M V Rao, B R Garg, C Ratnakar
Abstract
Occurrence of bullae in leprosy is a rare phenomenon. They can appear in the purpuric, painful, red patches of lucio phenomenon and in the erythema nodosum leprosum (ENL) lesions occurring during type 2 lepra reaction (Pfaltzgraff & Bryceson 1985). Generalized bullous drug eruptions due to rifampicin and DDS have also been reported in leprosy (Nigam et al 1979, Dutta 1980). Sometimes, bullous reactions may be localized to pre-existing leprosy lesions of borderline leprosy (Pfaltzgraff & Bryceson 1985, Periaswamy & Rao 1985, Singh 1987). Interestingly, Rodriguez and Wade (1945) and Job (1960) have recorded them in tuberculoid leprosy and lepromatous leprosy respectively. We report here a 60 year-old male suffering from lepromatous leprosy and bullous pemphigoid. This association seems fascinating for no such report thus far is available in the literature.
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Occurrence of bullae in leprosy is a rare phenomenon. They can appear in the purpuric, painful, red patches of lucio phenomenon and in the erythema nodosum leprosum (ENL) lesions occurring during type 2 lepra reaction (Pfaltzgraff & Bryceson 1985). Generalized bullous drug eruptions due to rifampicin and DDS have also been reported in leprosy (Nigam et al 1979, Dutta 1980). Sometimes, bullous reactions may be localized to pre-existing leprosy lesions of borderline leprosy (Pfaltzgraff & Bryceson 1985, Periaswamy & Rao 1985, Singh 1987). Interestingly, Rodriguez and Wade (1945) and Job (1960) have recorded them in tuberculoid leprosy and lepromatous leprosy respectively. We report here a 60 year-old male suffering from lepromatous leprosy and bullous pemphigoid. This association seems fascinating for no such report thus far is available in the literature.
Key concepts: Leprosy, Medicine, Lepromatous leprosy, Dermatology, Bullous pemphigoid, Dapsone, Rifampicin, Clofazimine