Fibrinolysis in the Domestic Chicken (Gallus domesticus)

Summary 1. Spontaneous fibrinolysis has been demonstrated in the domestic chicken. 2. Lysis is dependent on optimum conditions both in the euglobulin lysis time and fibrin plate techniques. High ionic strength buffers increase the lysis time as does a low molarity of CaCl2. A combination of the two greatly reduces the sensitivity of the tests. Absence of Ca++ from the standard fibrin plate prevented lysis from taking place. 3. The euglobulin precipitate of chickens contains almost all of the plasma fibrinogen. This would suggest that euglobulin lysis times are influenced by plasma concentrations of fibrinogen.