1968•Thrombosis and HaemostasisRequires access
Investigation of the Apparent Thrombogenicity of Thrombin
E.T. Yin, Stanford Wessler
Open publisher page 17 citations
Abstract
Summary This investigation demonstrates that most of the thrombogenic effect of small amounts of commercial thrombin is not dependent upon the calculated units of infused thrombin but rather upon its contamination with activated factor X. These data also reflect the need to re-evaluate the biologic effects attributed to thrombin itself in various studies in which thrombin preparations contaminated with activated factor X have been employed.