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[Interventional therapy of hepatic artery-portal vein fistula with gelatin sponge and lipiodol].

Haifeng Xu, Ren-jie Yang, Hui Chen, Xu Zhu

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Abstract

OBJECTIVE: To observe and compare the revasculation rate after embolization of hepatic artery-portal vein fistula (APVF) by gelatin sponge versus gelatin sponge with lipiodol. METHODS: The clinical data of 51 patients were retrospectively analyzed. They were divided into Groups A and B. APVF was embolized by gelatin sponge alone in Group A and gelatin sponge with lipiodol in Group B. Then the investigators observed and compared the revasculation rate of hepatic artery-portal vein fistula at Days 30 - 40 and 60 - 70 post-embolization respectively. RESULTS: There was no statistical difference in age, gender, pathological types and hepatic functions before intervention between Groups A and B. One of 28 APVF sites was embolized unsuccessfully in Group A while all APVF cases were embolized successfully in Group B. The revasculation rate of hepatic APVF were 70.37% and 46.15% at Days 30 - 40 post-embolization in Groups A and B respectively (χ(2) = 4.25, P = 0.039, chi-square test); the revasculation rates of APVF were 92.59% and 88.46% respectively at Days 60 - 70 post-embolization (P = 0.67). CONCLUSION: Interventional therapy of hepatic APVF by gelatin sponge and lipiodol is a safe method of reducing the short-term revasculation rate. It may be employed in clinical practices to save precious time for controlling hepatic malignant tumors.

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OBJECTIVE: To observe and compare the revasculation rate after embolization of hepatic artery-portal vein fistula (APVF) by gelatin sponge versus gelatin sponge with lipiodol. METHODS: The clinical data of 51 patients were retrospectively analyzed. They were divided into Groups A and B. APVF was embolized by gelatin sponge alone in Group A and gelatin sponge with lipiodol in Group B. Then the investigators observed and compared the revasculation rate of hepatic artery-portal vein fistula at Days 30 - 40 and 60 - 70 post-embolization respectively. RESULTS: There was no statistical difference in age, gender, pathological types and hepatic functions before intervention between Groups A and B. One of 28 APVF sites was embolized unsuccessfully in Group A while all APVF cases were embolized successfully in Group B. The revasculation rate of hepatic APVF were 70.37% and 46.15% at Days 30 - 40 post-embolization in Groups A and B respectively (χ(2) = 4.25, P = 0.039, chi-square test); the revasculation rates of APVF were 92.59% and 88.46% respectively at Days 60 - 70 post-embolization (P = 0.67). CONCLUSION: Interventional therapy of hepatic APVF by gelatin sponge and lipiodol is a safe method of reducing the short-term revasculation rate. It may be employed in clinical practices to save precious time for controlling hepatic malignant tumors.

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Available abstract

OBJECTIVE: To observe and compare the revasculation rate after embolization of hepatic artery-portal vein fistula (APVF) by gelatin sponge versus gelatin sponge with lipiodol. METHODS: The clinical data of 51 patients were retrospectively analyzed. They were divided into Groups A and B. APVF was embolized by gelatin sponge alone in Group A and gelatin sponge with lipiodol in Group B. Then the investigators observed and compared the revasculation rate of hepatic artery-portal vein fistula at Days 30 - 40 and 60 - 70 post-embolization respectively. RESULTS: There was no statistical difference in age, gender, pathological types and hepatic functions before intervention between Groups A and B. One of 28 APVF sites was embolized unsuccessfully in Group A while all APVF cases were embolized successfully in Group B. The revasculation rate of hepatic APVF were 70.37% and 46.15% at Days 30 - 40 post-embolization in Groups A and B respectively (χ(2) = 4.25, P = 0.039, chi-square test); the revasculation rates of APVF were 92.59% and 88.46% respectively at Days 60 - 70 post-embolization (P = 0.67). CONCLUSION: Interventional therapy of hepatic APVF by gelatin sponge and lipiodol is a safe method of reducing the short-term revasculation rate. It may be employed in clinical practices to save precious time for controlling hepatic malignant tumors.

Key concepts: Lipiodol, Gelatin sponge, Medicine, Embolization, Hepatic artery embolization, Fistula, Vein, Artery

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[Interventional therapy of hepatic artery-portal vein fistula with gelatin sponge and lipiodol]. — Research Paper | ScholarLens