Properties of hepatic tissue extracts: 2. An approach to the artificial liver.
Kotaro Mizuno, Tomoyuki Goya, Hiroshi Kimurâ, T Inou
Abstract
Kotaro Mizuno, Tomoyuki Goya, Hiroshi Kimurâ, T Inou
Abstract
In the previous paper [3], the lethal effect of normal rabbit liver extract intravenously infused into rabbits was described. By comparing to the course of destruction of the liver tissue in fulminant hepatitis, the toxicity of the liver extract was recently studied. Attempts were also made to adsorbing the liver extract by activated clay and detoxifying the liver extract with a formaldehyde solution, and the results suggested that the findings would be applicable as an approach to the artificial liver.
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In the previous paper [3], the lethal effect of normal rabbit liver extract intravenously infused into rabbits was described. By comparing to the course of destruction of the liver tissue in fulminant hepatitis, the toxicity of the liver extract was recently studied. Attempts were also made to adsorbing the liver extract by activated clay and detoxifying the liver extract with a formaldehyde solution, and the results suggested that the findings would be applicable as an approach to the artificial liver.
Key concepts: Liver tissue, Artificial liver, Toxic hepatitis, Fulminant hepatic failure, Hepatitis, Formaldehyde, Toxicity, Liver toxicity