[In vitro studies on amplification of rat erythropoiesis (author's transl)].
Charles E. Mize, Michel Prenant, N Pourreau, MARCEL C. BESSIS
Abstract
Charles E. Mize, Michel Prenant, N Pourreau, MARCEL C. BESSIS
Abstract
From rat bone marrow in which erythropoiesis has been depressed (by suppression of erythropoietin production), liquid culture has yielded a predominantly synchronous amplification of erythroblast development. Groups of 2, 4, 8, 16 and 32 erythrolbasts are observed at 9-15 hour intervals in successive stages of maturation, similar (by their staining characteristics and nuclear size) to that seen in vivo.
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From rat bone marrow in which erythropoiesis has been depressed (by suppression of erythropoietin production), liquid culture has yielded a predominantly synchronous amplification of erythroblast development. Groups of 2, 4, 8, 16 and 32 erythrolbasts are observed at 9-15 hour intervals in successive stages of maturation, similar (by their staining characteristics and nuclear size) to that seen in vivo.
Key concepts: Erythropoiesis, Erythroblast, Erythropoietin, In vitro, Staining, In vivo, Bone marrow, Andrology