[Pancreatic atrophy: its effect on the plasma concentration of pancreatic polpeptide, gastrin and motilin in dogs].

One hour postprandial responses of plasma concentrations of pancreatic polypeptide, gastrin and motilin were detected in healthy dogs. Pancreatic atrophy was produced in these animals by obstructing their pancreatic juice flow. Basal hormone concentrations in four animals did not change significantly during 11 months of pancreatic atrophy. During this period the animals displayed a significant postprandial response. These preliminary results suggest that hormonal mechanisms involved in the digestive process are maintained during pancreatic atrophy.