2018Experimental and Clinical TransplantationRequires access

Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature.

Arzu Velioğlu, Emel Eryüksel, Çağatay Çimşit, Serhan Tuğlular, Çeti̇n Özener

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Abstract

The use of inhibitors of mammalian target of rapamycin is associated with adverse pulmonary effects. Although sirolimus-related pneumonitis has been well described, reports on pneumonitis with everolimus are scarce. We report a case of everolimus-induced pneumonitis in a renal transplant recipient 5 years after initiation of everolimus treatment, and we also review the literature regarding everolimus-induced pneumonitis in renal transplant patients.

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What this paper is about

The use of inhibitors of mammalian target of rapamycin is associated with adverse pulmonary effects. Although sirolimus-related pneumonitis has been well described, reports on pneumonitis with everolimus are scarce. We report a case of everolimus-induced pneumonitis in a renal transplant recipient 5 years after initiation of everolimus treatment, and we also review the literature regarding everolimus-induced pneumonitis in renal transplant patients.

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OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The use of inhibitors of mammalian target of rapamycin is associated with adverse pulmonary effects. Although sirolimus-related pneumonitis has been well described, reports on pneumonitis with everolimus are scarce. We report a case of everolimus-induced pneumonitis in a renal transplant recipient 5 years after initiation of everolimus treatment, and we also review the literature regarding everolimus-induced pneumonitis in renal transplant patients.

Key concepts: Everolimus, Pneumonitis, Medicine, Renal transplant, Sirolimus, Interstitial pneumonitis, Adverse effect, Internal medicine

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Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature. — Research Paper | ScholarLens