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[Effect of adrenaline on the proliferation of the tunica media smooth muscle cells of rat aorta in culture].
Nelly Blaes, M.C. Bourdillon, B Crouzet, A Suplisson, J P Boissel
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Abstract
The proliferation of Rat medial aortic smooth muscle cells in secondary cultures is increased with adrenalin. The maximal effect is obtained after 3 days and the increase is dose-dependent. Thus adrenalin might be one of the factors responsible for the proliferation of smooth muscle cells that could play a key role in the formation of the atherosclerotic plaque in vivo.