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Combined cyclosporin-A and methylprednisolone treatment of Graves' ophthalmopathy.

Andras Leovey, Gyula Bakó, J Szabó, K Kálmán, Éva Fórizs

Abstract

Twelve patients with Graves' ophthalmopathy (grade 1-6, ATA classification) were treated with Cyclosporin-A, systemically in combination with methylprednisolone. We observed slight or moderate favourable effect in 9 cases. Our data suggest that the benefit was due to the methylprednisolone, the effectivity of which was enhanced by the cyclosporin even in the glucocorticoid-resistant cases.

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Available abstract

Key concepts: Methylprednisolone, Graves' ophthalmopathy, Medicine, Glucocorticoid, Internal medicine, Dermatology, Graves' disease, Disease