[Evaluation of the curative effect of combination chemotherapy with cisplatin plus radiotherapy in patients with advanced non-small cell lung cancer.].

BACKGROUND: To evaluate the curative effect of combination chemotherapy with cisplatin plus radiotherapy for advanced non-small cell lung cancer. METHODS: Fifty-eight patients with advanced non-small cell lung cancer were treated by combination chemotherapy with cisplatin plus radiotherapy as study group , and another 29 patients given radiotherapy only as control group. RESULTS: CR , CR + PR and PD in the study group were 55. 2 %(32/58) , 65. 5 %(38/ 58) , 8. 6 %(5/ 58) , and 24. 1 %(7/ 29) , 31. 0 %(9/ 29) , 44. 8 %(13/ 29) in the control group respectively. There were remarkable differences between the two groups ( P < 0. 01) . The 1 , 2 and 3 year survival rates in study group were significantly higher than those of control group ( P < 0. 01) . CONCLUSIONS: Combination chemotherapy with cisplatin plus radiotherapy is helpful to improving curative effects and survival rates in patients with advanced non-small cell lung cancer , and it should be spread in clinical practice.