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[Substrate specificity of monoamine oxidase from the brain and liver of the human fetus during antenatal ontogenesis].

T G Skorobogataia

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Abstract

Dynamics of changes in the monoaminooxidase activity with respect to different substrates is characterized by a number of peculiarities and varies essentially in the process of ripening of the organs. Both in the brain and in the liver tyramine (a substrate of enzymes of types A and B), serotonin and norepinephrine (substrates of type A) and benzyl amine (substrate of type B) are subjected to oxidative deamination: tyramine--most intensely, serotonin and norepinephrine--less intensely and benzyl amine--least intensely.

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Dynamics of changes in the monoaminooxidase activity with respect to different substrates is characterized by a number of peculiarities and varies essentially in the process of ripening of the organs. Both in the brain and in the liver tyramine (a substrate of enzymes of types A and B), serotonin and norepinephrine (substrates of type A) and benzyl amine (substrate of type B) are subjected to oxidative deamination: tyramine--most intensely, serotonin and norepinephrine--less intensely and benzyl amine--least intensely.

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Available abstract

Dynamics of changes in the monoaminooxidase activity with respect to different substrates is characterized by a number of peculiarities and varies essentially in the process of ripening of the organs. Both in the brain and in the liver tyramine (a substrate of enzymes of types A and B), serotonin and norepinephrine (substrates of type A) and benzyl amine (substrate of type B) are subjected to oxidative deamination: tyramine--most intensely, serotonin and norepinephrine--less intensely and benzyl amine--least intensely.

Key concepts: Oxidative deamination, Tyramine, Monoamine oxidase, Serotonin, Norepinephrine, Substrate (aquarium), Fetus, Biogenic amine

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[Substrate specificity of monoamine oxidase from the brain and liver of the human fetus during antenatal ontogenesis]. — Research Paper | ScholarLens