Haematuria and proteinuria in urinary schistosomiasis: response to therapy with praziquantel in Tanzanian children.

In order to assess the efficacy of praziquantel against Schistosoma haematobium and its effect on the morbidity indices, haematuria and proteinuria, a study was carried out using school receiving praziquantel at 40 mg/kg body weight. Twenty-four weeks after treatment, the percentage of cure was high and reached 100% among the 'light' and 'moderate' infection groups. In the 'heavy' infection group, a cure rate of 50% and a 69.3% egg reduction was observed. An overall cure rate of 94% was achieved at 24 weeks. Microhaematuria and proteinuria were reduced by 96.6% and 92.5%, respectively.